04 Dec 2023
30 Nov 2023
COVID-19 patients with ARDS who are admitted to the ICU needed tracheal intubation and mechanical ventilation, where the tracheal intubation strategy as early as possible with the good protocol ventilation management produce favorable patient outcomes. In performing the intubation needed to consider the right time to produce optimum outcome. The increase of Surfactant Protein-D serum level is a specific indicator of lung injury with severe ARDS and the duration of intubation. From that, the aims of this study to determine the correlation between Surfactant Protein-D (SP-D) and intubation time on COVID-19 patients. This observational analytic research with retrospective cohort design is conducted during March-August period and has obtained the ethics certificate from the Ethical Committee of Dr. Soetomo Surabaya. The examination of Surfactant Protein-D level is conducted on patients who have met the inclusion and exclusion criteria and the intubation time is recorded. In this research obtained 28 patients, where 20 patients are male and 8 patients are female. The comorbid factor that most affect the patient’s condition is Diabetes Mellitus. The average of Surfactant Protein-D serum level is 42,15 ng/ml (SD ± 32,71 ng/ml). The statistics analysis results showed that there is no meaningful correlation between Surfactant Protein-D serum level and intubation time (p: 0,304). In addition, it is also found that the SP-D level results which has no meaningful difference in the group of patients who died and survived (p: 0,159). The examination of Surfactant Protein-D level did not show a meaningful correlation with intubation time on Covid-19 patients.
This study investigated the effect of V. amygdalina on the hematological parameters and kidney function in Wistar rats exposed to stress. 25 Wistar rats were randomly assigned to five groups. NCG (control) was given water only, T1S0 was given V. amygdalina extract but not stressed, T2S24, T3S36, and T4S48 were given same concentration of V. amygdalina extract (100mg/kgBW) and stressed for 24hours, 36 hours and 48hours respectively. Hematological test was carried out by Mindray Haematology Analyzer BC-2800 and creatinine/urea tests were performed using Randox method. The result reveals increased WBC count in all treatment groups, which was significant only (P<0.05) in treatment group T4S48=21.28x103/mm3. The Hb concentration significantly increased in T1S0=14.86 x103/mm3 and T2S24=14.88 x103/mm3 respectively. There was significant (P<0.05) increase in serum creatinine (T1F0=0.196*, T2F24=0.191* and T3F36=0.175*) and urea concentration (T1S0=52.1* and T2S24=48.6*) when compared with their control. The result further revealed that increased duration of fasting stress progressively decreased serum creatinine (T2F24=0.191, T3F36=0.175 and T4F48=0.164) and urea (T2S24=48.6, T3F36=36.4 and T4S48= 26.0) concentration. These findings indicates that the boiled bitter leaf extract is able to improve hematological parameters but may compromise kidney function and that increased duration of fasting may have some reno-protective effects.
Malnutrition has long known as an unfavorable outcome in congenital heart disease patients. Malnutrition may be differentiated into underweight, stunting, and wasting depending on anthropometric measurement. The difference of malnutrition prevalence and its subtypes in acyanotic and cyanotic congenital heart disease is currently unknown. This systematic review aims to elucidate the incidence of malnutrition, stunting, wasting, and underweight in cyanotic and acyanotic congenital heart disease (CHD) children. This systematic review is written in accordance with PRISMA guideline. Studies were searched on five different databases, and only cohort or case control studies are selected. The search was done using combinations of keywords and MeSH terms whenever eligible. Statistics was calculated by fixed-effect model with the Mantel-Haenszel method when there was no significant heterogeneity or with DerSimonian- Laird weights for the random-effects model when there was a significant heterogeneity. Two case control studies are included for review. No difference of general malnutrition and wasting prevalence between acyanotic and cyanotic CHD group. Stunting is substantially more prevalent in cyanotic CHD group (p=0,05). Underweight is more prevalent in acyanotic CHD, however the difference is not significant (p=0,11) Stunting represent a more severe impact in cyanotic CHD.
Consciousness about HIV/AIDS and STIs has become one of today major challenges. The aim of this study was to identify the risk factors associated with awareness about HIV/AIDS and STDs among women in Bangladesh. To conduct this cross-sectional study, data were gathered from the Bangladesh Demographic and Health Survey (BDHS) 2014. The total number of women participants was 17,684 from seven divisions of Bangladesh: Dhaka, Rajshahi, Rangpur, Chittagong, Barisal, Khulna, and Sylhet. The prevalence of consciousness about HIV/AIDS and STIs among women in Bangladesh is 50.1% and 51.2%, respectively. The 2 test showed that the respondent’s age, place of residence, educational level, geographical difference, socio-economic status, radio, and television had a significant association with consciousness about HIV/AIDS and STIs. The multiple logistic regressions identified the risk factors – age of respondents, place of residence, educational level, socioeconomic status, geographical difference, listening to the radio, and watching television (TV) – with the consciousness among women in Bangladesh about HIV/AIDS and STIs. It is essential to increase the educational programmes concerning HIV/AIDS and STIs for rural areas in Bangladesh, especially for the younger women (<25 years). Radio and television play significant roles in increasing consciousness regarding HIV/AIDS and STIs in the rural areas of Bangladesh. The Bangladesh Government should consider including information about HIV/AIDS and STIs in primary and secondary school textbooks.
Recent COVID-19 pandemic is a global condition emerged from China, putting a major psychological distress among the key population associated with various level of interventions is one of the great the concern. Regardless of the socio-economic conditions in all the territory, the population can be differentiated based on the most and key risk of infection. Various measures have been suggested to control the pandemic stress from the key population at the psychological crisis interventions of COVID-19, including the provision of clinical psychological department at the clinical level, distance counselling to the affected people, the online support system at the community and national level for the prevention of the current scenario of the pandemic. To mitigate the COVID-19 related distress among the key population, a focus should be given at the multi-tiered, interactive, sustained psychological and counselling intervention strategies for reducing the long term impact.