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31 Jan 2023 (Vol 46 , Iss 02 )

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31 Jan 2023 (Vol 46 , Iss 01 )


Teikyo Medical Journal

Journal ID : TMJ-10-10-2022-11418
Total View : 456

Title : The Effects of Sleep Deprivation on Academic Performance of Health Sciences Students in Kuala Lumpur: An Institutional Study

Abstract :

Adequate and efficient sleep plays a crucial role in memory and learning. Thus, it is so important for students to have adequate and efficient sleep to perform well in academics. This cross-sectional study was conducted to investigate the correlation between sleep quality and academic performance of undergraduate students from health-science-related courses attending a public institution in Kuala Lumpur, Malaysia. 395 students from the faculty of Dentistry, Pharmacy and Allied Health were randomly selected and approached via email for participation in the study. Consented students were given a set of questionnaires through the Google Form, consisting of information regarding their demographic data, grade point average (GPA) of last semester and Pittsburgh Sleep Quality Index (PSQI) questionnaire. Collected data were analysed using Statistical Package for the Social Sciences (SPSS) software. The correlation between the global PSQI scores and the GPA of the students from each faculty was determined using Spearman’s rank coefficient correlation. Majority of the students across the faculties reported good sleep quality, good sleep efficiency, minimal sleep alteration and not taking any substance to help them to sleep better. 79.6 % of students from the Faculty of Pharmacy reported a global PSQI score of >5, followed by the Faculty of Allied Health (76.2%) and Faculty of Dentistry (66.4%). Mean GPA for all students lies within the excellent and good category. Only students from the Faculty of Pharmacy showed a weak negative correlation between the global PSQI scores and GPA, rs(98) = 0.266, p=0.008.

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Journal ID : TMJ-10-10-2022-11416
Total View : 447

Title : Angiogenesis around dental implants augmented by autogenous, xenogenous, and synthetic bone graft materials: an animal study in dogs

Abstract :

There is little information concerning the angiogenesis process around different graft materials. This animal study aimed to evaluate the expression of selected angiogenesis markers in extensive bone defects subjected to a concurrent implantation and grafting procedure with bovine bone graft or an alloplastic material, as compared to the autogenous bone. Thirteen dogs were distributed into three groups according to the time of sacrificing (2, 4, and 6 months). Extensive osteotomies were designed in the dogs' sternum, and the implants were placed in the bone defects. Each group of animals contained three subgroups according to the grafting material utilized (autogenous, xenogenous, or synthetic). At the end of the healing periods, the dogs were sacrificed and the osteograft blocks surrounding the implants were resected and submitted to a real-time polymerase chain reaction (PCR) assay to measure the expression of selected angiogenesis genes (VEGF-A, VEGFR, ANG2, TIE1, bFGF, and CD34). The two-way ANOVA revealed no significant interaction between the two factors graft materials and healing intervals (P>0.05). There was no significant difference among the grafting substitutes concerning the expression of VEGF-A, VEGFR, ANG2, TIE1, bFGF, and CD34 (P>0.05). Furthermore, no significant difference was found in the expression of angiogenesis genes between the 2-, 4-, and 6-month groups (P>0.05). Concerning the comparable expression of angiogenesis markers around dental implants, both Cerabone and Osteon can be regarded as suitable alternatives to the autogenous bone for filling the bony defects.

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Journal ID : TMJ-07-10-2022-11415
Total View : 382

Title : Case report: Evaluation of socket shield technique (SST) VS. Conventional Immediate implant placement in esthetic zone

Abstract :

Bone resorption and gingival recession after dental implant placement consider a big challenge to physician specially in the esthetic zone, so many techniques have been developed to preserve hard and soft tissues, Socket shield Technique preserve bone and gingival tissue by maintaining blood supply and periodontal ligament in implantation site. Evaluate the Hard and Soft tissues in this case of post extraction and immediate implant placement by applying socket shield technique comparing with traditional technique. This clinical case was carried at department of oral and maxillofacial surgery at Hama university. This study included two implant of post extraction and immediate implant placement at same patient. The age of patient was 22 years. The case was divided into two techniques, first implant: traditional Postextraction and immediate implant placement, second implant was Postextraction and immediate implant placement applied with socket shield technique (SST) bone graft was applied with temporized prosthetic fabricated by using the same crowns natural teeth, final prosthetic crown and functional loading were done according to ISQ values, The Hard and Soft tissues preservation were observed after 3 and 6 months of surgery. There was difference in comparison of soft tissue (PES) Index between two techniques (SST and conventional) according to the time on 3 month and 6 months, (SST) Helped to maintain soft tissues at 3 and 6 months after surgery more than conventional technique. So according to final soft tissue appearance on 6 months follow up we found that SST is safe and provides better esthetic results compared with the conventional technique in radiographic variable marginal bone lose of socket shield technique showed a difference (0.13 mm) after three months and (0.2 mm) after six months of surgery so SST is good technique and helps to maintain alveolar ridge at immediate implant placement sites, compared with the conventional technique showed a difference (0.38 mm) after 3 months and (0.75 mm) after 6 months, so SST had maintained the vascular supply with the help of the remaining PDL and provided better results. This article showed that socket shield is a sensitive technique and have a positive effect in preserving of gingival tissues and bone through follow up time and better than conventional technique. So, it is recommended to use SST because it provides good esthetic results in immediate implant placed in esthetic anterior region.

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Journal ID : TMJ-04-10-2022-11414
Total View : 479

Title : Evidence fore no involvement of cytomegalovirus in prostate cancer

Abstract :

Prostate cancer (PCa) is the cancer that registers the highest incidence and mortality rate in men. Epidemiological studies indicate the existence of an association between high exposure to Sexually transmitted diseases (STDs) and an increased risk of prostate cancer. Cytomegalovirus (CMV) is a member of the sexually transmitted herpesviridae family. Studies carried out on prostate biopsies revealed the presence of the virus on pre-neoplastic and neoplastic tissues. Thus, and given that the virus is transmissible through all body fluids including saliva and breast milk, our study aims to detect CMV in the blood of subjects with prostate cancer looking for a possible association between the infection and the risk of prostate cancer. Blood samples were collected from a population of 45 people with prostate cancer, viral DNA testing was performed using conventional PCR. We were unable to detect CMV DNA in the blood samples studied. Based on these results, a first suggestion to be made is the non-implication of CMV in prostate cancer. But, considering that the results of previous studies are controversial between detection and and non-detection of the virus, it would be opportune to increase the sample size and to consider other parameters related to the therapy administrated for a possible correlation between the anti-cancer protocol that can cause both immunosuppression and the reactivation of CMV of its latency.

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Journal ID : TMJ-03-10-2022-11411
Total View : 405

Title : The significant role of laboratory technician in covid-19, article review

Abstract :

The healthcare system has, over the years, undergone myriad changes aimed at improving its efficiency and quality levels. At the core of the changes are the concerted efforts of practitioners who work in tandem to deliver efficient services. Laboratory technicians are identified as vital cogs in the healthcare system as they work behind the scenes conducting tests that improve the validity of medical diagnoses. The important role of laboratory technicians came into the limelight during the coronavirus pandemic, which wreaked havoc worldwide. The novel nature of the SARS-CoV-2 virus necessitated prompt testing and evaluation of samples to understand its impact on the body, trajectory, and viable intervention mechanisms. This literature review aims to break down the roles of laboratory technicians during the pandemic. A total of 15 sources have been reviewed, which allude that the laboratory technicians were responsible for running tests and reviewing their quality and ingenuity. The insight derived from the tests permitted physicians and doctors to formulate clinical diagnoses that reduced the deleterious effects of the coronavirus. Consequently, the results indicate that the laboratory technicians tested biomarkers that determined the risk of contracting or transmitting the SARS-CoV-2 virus in specific populations. Identifying risk biomarkers facilitated the creation of preventive mechanisms and doling out recommendations, thus minimizing morbidity and mortality rates. Moreover, the practitioners played an advocacy role during the pandemic by calling for new technologies and testing procedures that could cope with the epidemiological response needs. The technologies created a conducive milieu for the collection, storage, and subsequent testing of samples, thus reducing the probability of errors. Conclusively, the literature review indicates that the role played by the practitioners helped identify vaccines that quelled the continuous spread of the virus.

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