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21 May 2022 (Vol 45 , Iss 04 )

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31 May 2022 (Vol 45 , Iss 03 )

Journal ID : TMJ-19-08-2021-10593
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Title : The value of Serum Anti-Chlamydia trachomatis Ig G Antibody testing in predicting Tubal Factor Infertility

Abstract :

Infertility is increasingly becoming a significant health problem in many areas of the world. The purpose of this study was to investigate the role of Serum Anti Chlamydia Trachomatis Ig G antibody serology as a screening test for tubal infertility and to compare the result with hysterosalpingography (HSG). Prospective cross-sectional study, Serum Chlamydia trachomatis immunoglobulin G antibody test were determined prospectively in 192 infertile patients by using ELISA test, the results of testing will compared with the results of HSG with respect to their predictive value of tubal factor infertility. A positive CAT had 32.4% sensitivity and 83.2% specificity at detecting tubal disease with a positive predictive value of 31.6% and a negative predictive value of 83.8%. There was statistically significant difference between age and type of infertility. In secondary infertility women, the sensitivity of CAT 40.0% and 81.4% specificity for detecting tubal disease with a positive predictive value of 35.3% and a negative predictive value of 84.2%. The LR+ of CAT was 2.15 while the LR- 0.74. These finding highlighted a correlation between the tubal factor and the anti-chlamydial antibodies. CAT is poorly sensitive and highly specific.

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