Title : The Coronavirus Disease 2019 (COVID-19) Vaccine in Pregnancy: A Review of Current Evidence and Researches in Indonesia

Vaccination in pregnancy is a unique case in that there is additional consideration for the fetus. Meanwhile, the immunological adjustment made to facilitate the fetus also renders pregnant women more susceptible to infections, such as Coronavirus Disease 2019 (COVID-19), with worse outcomes. In low- and middle-income countries, including Indonesia, pregnant women also have a higher risk for death of COVID-19. Furthermore, the emergence of a new variant also raises concerns of a setback in vaccinations. In this review, current evidence related to COVID-19 vaccination in pregnancy, such as efficacy, safety, and transfer of maternal antibodies is evaluated. In addition, existing knowledge gaps regarding COVID-19 vaccination in pregnancy are also explored in this review.