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05 Jul 2022 (Vol 45 , Iss 05 )

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31 Jul 2022 (Vol 45 , Iss 05 )

Journal ID : TMJ-12-01-2022-10989
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Title : Synthesis, Characterization and Biological Activity of Schiff Bases Derived from Heterocyclic Compounds

Abstract :

In this paper, a series of new compounds were synthesized, yielding four compounds including two schiff bases. This compounds were synthesized from hetero cyclic isatin with 5-Amino-1,3,4-thiadiazole-2-thiol (I1-I4). Condensation of I2 compound with aromatic aldehydes such as 4-nitro benzaldehyde and 4-hydroxy benzaldehyde yielded schiff bases (I3 and I4). These compounds were characterize by FT-IR, 1H-NMR, and 13C-NMR. The physical properties were assessed. Biological activity of all of the synthesis compounds were investigated.

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