Abstract :
The hypokalemic periodic paralysis is a rare (1:100000) inherited channelopathy of skeletal muscles characterized by muscle weakness coinciding with low potassium levels, many classifications exist. However sporadic, familial, and thyrotoxic is the commonest, we presented a thirty-eight-year-old Filipino Female with sporadic periodic paralysis with quadriparesis. The literature of the published case reports, the genetic background, investigation, and treatment was reviewed.