Submission Deadline
05 Jul 2022 (Vol 45 , Iss 05 )

Upcoming Publication
31 Jul 2022 (Vol 45 , Iss 05 )

Journal ID : TMJ-17-05-2022-11288
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Title : Sensitivity and Specificity of Serological Test Compared to Real-Time Polymerase Chain Reaction (RT-PCR) in COVID-19 Patients

Abstract :

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a new coronavirus, which was first detected in Wuhan, China. The high number of cases and the rapid process of infection require fast and accurate detection to establish a diagnosis of COVID-19. The study aimed to obtain the sensitivity and specificity of the SARS-CoV-2 Architect IgG serological test compared to RT-PCR in COVID-19 patients. This study uses a cross-sectional approach to diagnostic testing, using 128 patients obtained at Persahabatan Hospital. This study took place from April 2021 to July 2021 at the Persahabatan Hospital. Patients swabs were taken for RT-PCR and blood drawn for serological testing using the Architect® i2000SR from Abbott. This study obtained Architect sensitivity results of 27.37% (18.72–37.48%) and specificity results of 63.64% (45.12–79.60%), as well as NPV of 23.33% and PPV of 68.42%. Serology tests using Architect have low sensitivity and specificity, so it cannot be used as a screening test in the population.

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