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23 Sep 2024 (Vol 47 , Iss 09 )

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31 Aug 2024 (Vol 47 , Iss 08 )

Journal ID : TMJ-05-03-2022-11173
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Title : Potential Anti-inflammatory Effect of Statin on Inflammatory Colitis Induced in Experimental Animals

Abstract :

Ulcerative colitis is a type of inflammatory bowel disease that is chronic, recurring, and remitting. Although the cause of colitis is uncertain, many studies have associated it with changes in immunity, genetics, and environmental factors. The increased proportion of unwanted effects, together with the current treatment's poor therapeutic effectiveness, suggests that new medications with fewer side effects and high effectiveness are needed. Efforts have accordingly been increased towards developing treatments by applying the strategy of " Drug Repurposing " through using existing drugs such as Atorvastatin for treatment of this disease outside the scope of original medical indication.

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