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20 May 2024 (Vol 47 , Iss 05 )

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31 May 2024 (Vol 47 , Iss 05 )

Journal ID : TMJ-12-11-2021-10792
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Title : Neutrophil to lymphocyte ratio and C-reactive protein level markers in severe COVID patients

Abstract :

Coronavirus infection was described as a highly transmitted strain. COVID is mainly transmitted between people by air droplet and direct contact. COVID is a disease characterized by highly inflammatory changes in the lungs. The complete blood count is the most available, easy, efficient, and economic laboratory test. And, total white blood cell (WBC) count and neutrophil -to-lymphocyte ratio (NLR) are indicators of the systematic inflammatory response. 50 patients were listed as severe infection had developed into severe infection (intensive care unit (ICU) admission) and 30 heathy individual as control group. Data for patients, such as age and gender, were collected. Blood samples s, including CBC with total WBC, differential counts, lymphocyte count, and neutrophil count were performed using 5-parts differential swelab autoanalyzer hematology. 50 COVID cases with mean age of 52.86 ± 13.9 (range: 29-80) years were recruited. Twenty-five (50%) cases were male and 50% were female with 30 normal healthy control group with mean age of 49.6 ± 14.8 years, 17 cases were male and 13 cases were female. There was significant difference between two groups in NLR, CRP. In this study the mean ±SD for NLR of the patients found to be very highly significant difference when compared with control group, at the level of significantly (<0.001) by student T Test. This study suggest that early identification of critical illness and risk stratification management will reduce mortality and help alleviate the burden on insufficient medical resources. Early diagnosis of patients with status have to worsen may help in get perfect care and optimizing the use of ICU.

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