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30 Jun 2024 (Vol 47 , Iss 06 )

Journal ID : TMJ-03-02-2022-11080
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Title : L-carnitine 's role in oxidative stress, as well as its role in disease and kidney and liver impacts

Abstract :

The following review tends to assess the role of L-carnitine relevant to biological role and biological properties and it role in suppression the oxidative stress L-carnitine has been shown to be useful in the treatment of coronary heart disease, as well as heart and renal failure characterized by increased oxidative stress in addition to its impact on kidney it also had crucial role on liver by L-carnitine might be a promising supplement to improve or delay the progression of liver disease Carnitine deficiency can arise in diseases including diabetes, sepsis, cardiomyopathy starvation, cirrhosis, endocrine disorders, and aging due to abnormalities in carnitine control. L-carnitine should be viewed along with doxorubicin, cisplatin, carboplatin, oxaliplatin, cyclophosphamide and ifosfamide to block their multiple organ toxicities and to permit larger doses of these anticancer drugs to be administered, thereby killing more cancer cells and increasing the chances of patient survival.

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