Abstract :
The Indonesian government has launched a program of Clean and Healthy Living Behavior (CHLB) (in Indonesian, namely of the program is Clean and Healthy Living Behavior or PHBS) that has been implemented, and can used to preventing Covid-19. So it is necessary to research knowledge, attitude and behavior of CHLB in carrying out health protocols to minimalize the Covid-19 period. This study is observational study with health cadre in Karanganyar, Sragen, and Sukoharjo district with purposive sampling to reach this sample. A total of 114 respondents and a complete questionnaire are 107, or response rate was 93.9%. The instruments was standardized Cronbach's Alpha (α =0.861). Data analyzed used descriptive statistics (percentage, mean, standard deviation). The average knowledge score was statistically significant (p < 0.05) varied by respondents' age, gender, education. The average score of attitudes toward COVID-19 was statistically significantly varied by educational attainment, occupation, and family income. The average score of preventive behavioral practices toward COVID-19 was statistically significantly varied by occupation. Knowledge, attitude, and behavior of CHLB in carrying out health protocols prevent Covids-19.