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27 Jun 2024 (Vol 47 , Iss 06 )

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30 Jun 2024 (Vol 47 , Iss 06 )

Journal ID : TMJ-23-12-2021-10923
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Title : In vitro anticancer activity of RA extracts of peppermint leaves against human cancer breast and cervical cancer cells

Abstract :

Natural product research provides a unique opportunity to test new anticancer agents while also learning about significant and relatively important modes of action. Aromatic rosmarinic acid (RA), which is an ester of caffeic acid and 3,4-dihydro-xyphenyllactic acid, has been claimed to have anti-inflammatory, anti-obesity and cancer prevention characteristics. It is found in the Lamiaceae family. The anticancer capacity of rosmarinic acid derived from (Peppermint) Mentha piperita L. was tested in vitro towards breast Cancer cells MCF7 cell line at range of concentrations 100,250,500,750,1000μg/ml and human Cervical cancer HeLa cell line at different concentrations of 100, 250, 500, and 1000 μg/ml. The growth of MCF-7 breast cancer cells was slowed down by RA at a concentration of 1000 g/ml, 48% and the growth of cervical cancer cells HeLa was inhibited by RA at a concentration of 1000 µg/ml only 1%.

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