Abstract :
The formation of the neuroimmuneedocrine (regulatory) system covers the prenatal period, proceeding under sterile conditions, and the postnatal period, under the influence of various microorganisms. In this work, using the example of non- microbial, mono-associated, contaminated with pathogenic and opportunistic microorganisms, the morphological features of the formation of the intestinal neuroimmune-endocrine system are considered. It, as an important component of the general regulatory system of the body, has a decisive influence on the structure and function of internal organs, interaction with the external environment. The paper considers modern methods of studying the properties of the neuroimmune endocrine system of the digestive system during the regulation of adaptation and homeostasis.