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02 Dec 2022 (Vol 45 , Iss 10 )

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30 Nov 2022 (Vol 45 , Iss 09 )

Journal ID : TMJ-11-09-2022-11398
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Title : Evaluation of the efficacy of botulinum toxin type A injection on improving the submandibular approach scars: Randomized controlled trial, Split-Scar

Abstract :

This study aims to evaluate the efficacy of early postoperative injection of botulinum toxin type A (BTA) on improving the submandibular approach scars. Fifteen patients who underwent facial surgery through the submandibular approach were enrolled in this study. On the seventh postoperative day, BTA was randomly injected into one-half of each wound. The other half was injected with the same amount of saline alone. The scars were assessed independently by three surgeons at one, three, and six months postoperatively using the visual analogue scale (VAS), the Vancouver Scar Scale (VSS), and the patient and observer scar assessment scale (PSAS and OSAS). All Fifteen patients have completed the clinical study according to the three follow-up periods. Compared to the half injected with saline only, the BTA treated side showed a noticeable improvement and statistically significant difference in most periods, especially at the six-month follow-up appointment. According to the used scales: VAS, VSS, PSAS and OSAS, the results of statistical tests after six months were as follows (P = 0.001, P = 0.009, P=0.004 P=0.001), respectively. BTA early injection into submandibular approach wounds leads to better-looking submandibular approach scars.

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