02 Dec 2022
30 Nov 2022
According to estimated albuminuria and glomerular filtration rate the kidney failure severity can be different. Mortality outcomes initially begin from a loss of access to renal replacement therapy specially in the developing states. The kidney failure classified as acute or chronic disease. In the body, urea is the main output of protein metabolism. The concentration of the urea plays significant role in the blood as an indicator of kidney functions. dehydration, gastrointestinal hemorrhage, renal disorders, high-protein diets, or elevating protein catabolism are the most causes of increasing urea in blood. The objective of this study was to investigate the assembly of the urea with kidney failure in Iraqi people. Biochemical study was performed on 20 kidney failure patients from Baghdad Surgical Hospital and 20 apparently healthy control. The concentration of urea in the serum was determined. Comparisons of studied parameters were done by statistical analysis system (SAS). The percentage of urea level was significantly (P≤0.01) greater in people with kidney failure disease compared with apparently healthy control (70.96 ± 9.17 versus 31.86 ± 3.44 respectively; Ttest=20.214, P-value =0.0006). No-Significant difference were noted between the level of urea and the age of both two group of patients and control (> 50= 45.36 ±8.57 versus ≥ 50= 58.57 ±9.15 respectively; Ttest=24.323, P-value =0.273). while, there were significant difference in male than female as related to serum level of urea (63.38±9.34 versus 39.45±7.15 respectively; Ttest=24.323, P-value =0.0435). We concluded that the increasing of serum urea is associated with kidney failure in Iraqi people.