The wound healing process after tooth extraction is expected to be faster and it can restore normal tissue function and reduce the risk of complications. Acceleration of the wound healing process can occur if the amount of oxygen in the tissue is achieved. Moderate-intensity continuous exercise can accelerate wound healing by increasing tissue oxygenation. Collagen requires oxygen in the process of procollagen formation in wound healing. To prove the difference in collagen density after tooth extraction in Wistar rats after continuous moderate-intensity swimming exercise. Wistar rats were divided into four groups, namely the control group on day 3 and 7 (K1 and K2), the treatment group on day 3 and 7 (K3 and K4). In groups K1 and K2 immersed in water in a bucket, groups K3 and K4 were given continuous moderate-intensity swimming exercise every day for 2 weeks. On the 15th day, the mandibular incisors of Wistar rats were extracted. Collagen density was observed on day 3 (K1 and K3), on day 7 (K2 and K4) after tooth extraction. The data were analyzed statistically using the Anova test. Statistical data showed there was a significant difference between all groups (p=0.000). Collagen density in the K4 group was higher when compared to the others. There is a difference in collagen density after tooth extraction in Wistar rats after continuous moderate-intensity swimming exercise.