Abstract :
Diabetic vitreopathy is the changes in the vitreous caused by diabetes mellitus (DM). To date, there are still no methods for the clinical registration of VB changes. The possibility of clinical registration of VB changes would allow studying its role in the development of diabetic changes in the retina and other intraocular structures. To carry out early detection of signs of diabetic vitreopathy in young patients with type 1 diabetes and the possible relationship of these changes with systemic and local factors. In 84 conditionally healthy individuals (168 eyes) and 127 patients with type 1 diabetes (254 eyes) aged 10 to 25 years, the density of the vitreous was studied according to multi-slice spiral computed tomography. In the observation groups, indicators of glycemia, indicators of lipid metabolism and other systemic and local indicators were studied. The study results showed that in patients with type 1 diabetes, an increase in the density of the vitreous in the central and preretinal regions is statistically significant. Among the systemic factors, only the indicators of glycemic metabolism were significant. Thus, multi-slice spiral computed tomography is a rather sensitive investigation method, making it possible to record a subtle difference in the density of the two main components of VB in conditionally healthy individuals and patients with type 1 diabetes. Changes in VB density are due to diabetes mellitus and an increase in carbohydrate metabolism, not postmortem changes.
