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18 Aug 2022 (Vol 45 , Iss 06 )

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31 Aug 2022 (Vol 45 , Iss 06 )

Journal ID : TMJ-14-04-2022-11250
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Title : Comparison study between Levels of thyroid autoantibodies (anti-thyroid peroxidase antibodies and thyroglobulin antibodies) and Thyroid hormones among women with Thyroiditis and Polycystic ovarian syndrome

Abstract :

Thyroid autoantibodies and thyroid hormones were examined in women with thyroiditis and polycystic ovary syndrome (PCOS). Measurement of anti-TPO; anti-Tgo; T3; T4 and TSH by double-sandwich Elisa technique. Current study showed no statistically significant difference between the Levels of TSH, T3, T4, concentration of Anti-Tg and Anti TPO in serum of Thyroid it is group and age groups (P=0.190, P=0.609, P=0.522, P=0.513 and P=0.718 respectively), but was no significant (P=0.919) difference between Control and Polycystic groups. Anti Tg level was no statistically significant difference between Control and Thyroiditis groups (P=0.853), but the difference between Control and Polycystic groups was highly statistically significant (P=0.000). Anti TPO level was no statistically significant difference between Control and Thyroiditis groups (P=0.335), also the difference between Control and Polycystic groups was no statistically significant (P=0.567), whilst highest level of TSH, T3. T4 and Anti Tg among Thyroiditis group [(8.20±5.60), (2.81±0.62), (2.81±0.62) and (0.32±0.24) respectively]. While level of Anti TPO (0.58±0.34) was higher in Control group, The levels of T4;TSH; Anti TPO and Anti-Tg were highest in Hypothyroidism cases [(10.42±5.87), (10.75±3.79), (0.38±0.28) and (0.64±0.39) respectively]. The highest levels of T3 and T4[ (2.86±0.87) and (12.70±3.05)] was in Hyperthyroidism cases. The difference were no statistically significant of all difference (T3, T4, Anti-Tg and Anti TPO) between Hypothyroidism and Hyperthyroidism of Thyroiditis group (P=0.726, P=0.159, P=0.057 and P=0.233 respectively), except the TSH level difference was highly statistically significant (P=0.002). No statistically significant difference between the Levels of TSH, T3, T4, concentration of Anti-Tg and Anti TPO in serum of Thyroid it is group and age groups. Anti Tg level was no statistically significant difference between Control and Thyroiditis groups, but the difference between Control and Polycystic groups was highly significant. also difference between Control and Polycystic groups, whilst highest level of TSH, T3,T4 and Anti Tg were among Thyroiditis group, WhileAnti-Tg and Anti TPOwere highest in Hypothyroidism. highest levels of T3 and T4 were in Hyperthyroidism cases, and no significant of all difference(T3, T4, Anti-Tg and Anti TPO) between Hypothyroidism and Hyperthyroidism of Thyroiditis group, except TSH.

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