Abstract :
The study was proposed to evaluate serum selenium, copper, zinc, vitamin C and E in benign prostatic hyperplasia patients in AL-Hilla city. The study comprises of a total 91 men which consist of patients and control groups, the patients group comprises 48 men with benign prostatic hyperplasia while the control group comprises 43 apparently healthy men. The study results revealed a significant reduction in serum selenium, zinc, vitamin C and E concentrations in BPH patients in comparison with those of control group and the copper/zinc ratio were significantly increased in BPH patients group in comparison with those of control group, while serum copper concentration were non-significantly increased in BPH patients group in comparison with those of control group. In conclusion, the decreasing of antioxidants in BPH resulting in imbalance between oxidant and antioxidant agents that increase the oxidative stress which may be important factor for development and exacerbation of BPH.