Abstract :
The incidence of postoperative AKI CABG with CPB at RSUD Dr. Soetomo Surabaya reached 69.8%. This study aims to analyze several risk factors that are still controversial, including: perioperative MAP, duration of CPB, plasma osmolarity, and GFR. This study is a prospective analytic observational cohort design conducted on CABG patients with the CPB technique without a history of previous kidney disease at RSUD Dr. Soetomo Surabaya in September-December 2020. Examination of risk factors was carried out before, during, and after surgery, until the patient was discharged from the hospital. There were 21 patients who entered the study. A total of 14 people (61.9%) were diagnosed as AKI after surgery, 11 people (78.6%) of whom were male. Patients with AKI had lower MAP at the time of surgery (79.9 ± 12.6) and after surgery (99.5 ± 13.0). Patients with AKI also experienced a longer duration of CPB (139.1±64.0), and also had a lower plasma osmolarity (315.2±60.7). These three factors were not statistically significant. A significant difference was only found in the lower eGFR (51.1±15.8) with a p-value of 0.005 and an AUC of 0.837. The cut-off value of eGFR was 63.3 with an OR of 22.0. Of all risk factors assessed, only eGFR was found to be an independent risk factor for AKI after cardiac surgery, especially CABG with CPB technique.
