Antibiotic resistance in pathogenic microorganisms is on the rise, prompting the development of novel antimicrobial options. Many plant components have received a lot of interest in Iraq as alternatives to traditional treatment. Two Iraqi medicinal plants, Olea europaea and Punica granatum, were examined in this study. One sort of solvent, hot boiled water, was used to extract the plant sample. The plant extract was tested as an antibacterial agent against Staphylococcus aureus, Klebsiella pneumoniae, Escherichia coli, and Pseudomonas aeruginosa in three concentrations (100, 150, and 200 mg/ml) using the agar-well diffusion method. Antibacterial activity was found in all of the tested plant extracts at various concentrations, and this activity varied based on the bacteria species, plant type, solvent type, and extract concentration. Plant extracts are more sensitive to Gram-positive bacteria than they are to Gram-negative bacteria, depending on the kind of bacterium. Increases in extract concentration, on the other hand, have been linked to an increase in the diameter of the inhibitory zone. Olea europaea extract generated the highest diameter inhibitory zone.