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27 Jun 2024 (Vol 47 , Iss 06 )

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30 Jun 2024 (Vol 47 , Iss 06 )

Journal ID : TMJ-03-04-2023-11522
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Title : ACCELERATION OF ALVEOLAR BONE DAMAGE IN PATIENTS WITH CHRONIC PERIODONTITIS DUE TO METABOLIC SYNDROME

Abstract :

Periodontitis is a health problem in the oral cavity that has a significant prevalence in Indonesia. Periodontitis cases have a greater risk in patients with metabolic syndrome. A literature review was carried out to prove the mechanism of accelerating alveolar bone destruction due to chronic periodontitis in patients with metabolic syndrome. The literature review is arrange by searching and selecting publications according to the literature criteria, the information obtained is secondary data. The selected articles were then categorized by discussing the mechanism of alveolar bone damage in chronic periodontitis due to metabolic syndrome. Increased glucose and fat levels in the metabolic syndrome trigger conditions of oxidative stress and induce increased levels of chemerin, ROS secretion, AGE, and pro-inflammatory cytokines, thereby accelerating the process of alveolar bone destruction in patients with chronic periodontitis.

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