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19 Apr 2024 (Vol 47 , Iss 04 )

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30 Apr 2024 (Vol 47 , Iss 04 )

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Teikyo Medical Journal


Journal ID : TMJ-22-11-2023-11587
Total View : 462

Title : Aminoglycoside resistance phenotype and genotype characteristics in Escherichia coli and Klebsiella pneumoniae: Interaction with an external clinical patient with an intraabdominal infection in Cipto Mangunkusumo National General Hospital (RSCM)

Abstract :

Southeast Asia has the highest risk of antimicrobial resistance (AMR). An intra-abdominal infection (IAI) in Indonesia is caused by E. coli and K. pneumoniae. This cross sectional descriptive analytical study, which conducted at Cipto Manunkusumo National General Hospital (RSCM) Jakarta, Indonesia, aimed to analyze aminoglycoside resistance in these bacteria and its impact on clinical digestive disorders. Samples were collected from IAI diagnoses between January 2019 to December 2020, and tests were performed in 2022-2023. The samples were sub-cultured on MacConkey media (35-37oC, 18-24 hours). The resulting colonies were identified with Gram staining and VITEK2 system. Isolates were tested for amikacin/gentamicin resistance with E-test. Of 79 isolates, 72.2% were E. coli and 27.8% were K. pneumoniae. A small percentage (6.3%) exhibited armA gene resistance. Patients with gentamicin resistance had a higher mortality rate (24.1%) compared to those without (14.7%), while amikacin resistance correlated with even higher mortality (40%). Risk factors like qSOFA, age, and amikacin resistance were statistically linked to clinical outcomes. The factors mentioned should be used cautiously as independent predictors, as they interact with external results. The researchers suggest that subsequent research should focus on improving PCR processes for greater accuracy and reducing errors.

Full article
Journal ID : TMJ-30-10-2023-11582
Total View : 380

Title : Knowledge and Attitude of Husbands Towards Postpartum Depression in Dammam, Khobar and Qatif, Saudi Arabia.

Abstract :

Postpartum depression (PPD) is a non-psychotic depressive disorder classified as an episode of major depression with onset within 4 weeks of childbirth. It is characterized by depressed mood, lack of interest or enjoyment in activities, appetite disturbance, sleep disturbance, fatigue, difficulty concentrating or making decisions, unnecessary guilt, feelings of worthlessness, and suicidal ideation following the birth of an infant. This study Aimed to assess the level of knowledge and attitude of husbands with regards to postpartum depression for female, in eastern province. Analytic cross-sectional study was conducted at primary health care centers in Dammam, Khobar, and Qatif, ministry of health, under E1 cluster in Saudi Arabia. Husbands of post-partum women was included in the study. The sample size was 423 husbands. Data was collected via a self-reported questionnaire. More than half of the participant husbands had inadequate knowledge (51.3%). Most of the participants didn’t know that poor education, young age of the mother and genetics (73.5%, 71.9% and 71.9% respectively) are risk factors of post-partum depression. While 52% didn’t know that death wishes are symptom of postpartum depression. Negative attitude was reported by 53.4% of the sample. The result showed that 72% of the participated husbands will seek needed assistance if their wives were diagnosed with postpartum depression. There was statistically significant difference between the educational level, monthly income and those had come across women with postpartum depression and the level of knowledge of the participants (p≤0.05). This study concluded that a significant proportion of the participants had inadequate knowledge and a negative attitude regarding postpartum depression. Therefore, husbands need health orientation and education about postpartum depression during their wives’ pregnancies and postpartum periods.

Full article
Journal ID : TMJ-27-10-2023-11581
Total View : 410

Title : The Coexistance of Condyloma Lata with Condyloma Acuminata in Teen Pregnancy : a Case Report

Abstract :

Syphilis and Human Papillomavirus (HPV) infection represent sexually transmitted infections (STIs) that are frequently encountered in Indonesia. Secondary syphilis can affect nearly all bodily structures, with one of its clinical manifestations being condyloma lata, which can resemble condyloma acuminata, a manifestation of Human Papilloma Virus (HPV) infection. The exact prevalence of coexistence between condyloma lata and acuminata remains uncertain. Considering that pregnancy constitutes an immunosuppressed state, the manifestations of HPV and syphilis may be more severe in pregnant women. A case is reported of a 17-year-old female, G1P0A0, with a gestational age of 17-18 weeks, presenting with the primary complaint of moist, malodorous nodules in the genital and buttock areas. The patient was diagnosed with a co-infection of syphilis and HPV, presenting simultaneously with large condyloma lata and condyloma acuminata clinical manifestations.

Full article

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