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Teikyo Medical Journal


Journal ID : TMJ-02-01-2023-11481
Total View : 461

Title : Thyroidectomy effects on weight and body mass index: A systematic review and meta-analysis

Abstract :

Thyroidectomy is common and is performed for malignancy, goiters with pressure symptoms, and certain types of Grave's disease. Weight and body mass index (BMI) following thyroidectomy were discussed controversially. This meta-analysis aimed to assess weight and MBI following thyroidectomy. A systematic literature search was conducted in PubMed, Medline, and Google Scholar with interest in articles that assessed body weight and body mass index following total or subtotal thyroidectomy. The search engine was limited to the period from inception up to October 2022. The keywords total thyroidectomy, subtotal thyroidectomy; Graves' disease, multinodular goiter, differentiated thyroid carcinoma, and toxic nodules were used. Out of the 634 articles retrieved, 89 full texts were screened, and only six studies (five retrospective and one prospective cohort) fulfilled the inclusion and exclusion criteria. No differences were evident regarding weight and BMI before and after thyroidectomy (odd ratio, -0.63, 95% CI, -1.50-0.24, P-value for overall effect, 0.15 and -0.12, 95% CI, -0.41-0.16, P-value for overall effect, 0.40 respectively. No heterogeneity was observed, I2 for heterogeneity, 0.0%. No association between thyroidectomy (when performed for differentiated thyroid carcinoma and hyperthyroidism), weight, and body mass index. Further studies assessing thyroid stimulating hormone levels, radioactive iodine therapy, and thyroxine dose are needed.

Full article
Journal ID : TMJ-28-12-2022-11476
Total View : 471

Title : Assessment of progastrin releasing peptide as a biomarker in early detection of non-muscle invasive bladder cancer patients; A prospective multicentric study

Abstract :

Bladder tumors are frequently diagnosed as urologic malignant diseases and mostly identified in their incipient form as non-muscle invasive. The diagnosis of bladder carcinoma at this moment is established using cytology and cystoscopy and is a great challenge for clinicians due to the lack of sensitivity and specificity. Biomarkers could improve and enhance the diagnosis and screening techniques. To evaluate the usefulness of serological and urological progastrin releasing peptide levels as a biomarker for the diagnosis of non-muscle invasive bladder cancer. In this study, Patients were first diagnosed pathologically at our teaching hospital and oncology center. Eighty subjects were recruited and divided into three groups: Ta Non-muscle invasive bladder cancer patients (n= 26), T1 Non-muscle invasive bladder cancer patients (n= 24) and thirty healthy control subjects. Serum and urine samples were collected from patients and had their serum progastrin releasing peptide levels measured using enzyme-linked immunosorbent assay. Statistical analyses were used to reveal the associations therein. Progastrin releasing peptide was significantly elevated in serum and urine of non-muscle invasive bladder cancer (Ta and T1) patients (P < 0.0001); compared to control group, but its levels were higher in Ta Non-muscle invasive bladder cancer than T1 Non-muscle invasive bladder cancer. Progastrin releasing peptide assay is a simple and inexpensive test, and might serve as a potential serological and urological biomarker for non-muscle-invasive bladder cancer patients, especially, in the early stages Ta Non-muscle invasive bladder cancer.

Full article
Journal ID : TMJ-28-12-2022-11475
Total View : 466

Title : The Effect of Applying the Program of the Continuous Medical Education on the Nursing Performance

Abstract :

This study examined the impact of HR's readiness to deploy CME on nursing staff performance. The study used these variables: Implementation of CME objectives, plan, teaching content, methodology, activities, and educational environment. The study employed a descriptive approach, and 208 personnel at Ohud Hospital in AlMadinah AlMunawarah city completed a questionnaire. After statistical analysis, the study found: On the axis (the plan), most respondents (3.9471) agree. They averaged 3.9247 on the axis (objectives) (agree). The axis showed respondents' answers (methods and activities). mean=3.87 The respondents' answers on the axis (educational environment) were (agree), with mean = 3.865 and standard deviation = 0.51452. Similarly, responses on the axis (educational material) averaged 3.8548 (I agree). The results suggested the following: The programmes should use practical ways in implementing the continuing medical education programme plan, as well as current and diversified activities and techniques connected to the activities and methods used. The lecture hall must have all components, such as support services for the CME programme plan, and the educational material must match the demands of the nursing staff. The educational atmosphere must give psychological comfort for the participants. And, the programme strategy and objectives must be flexible and adaptable, and employ modern and diversified activities and approaches related to education.

Full article
Journal ID : TMJ-28-12-2022-11474
Total View : 438

Title : THE VALUE OF THE BLOOD GROUP IN ECHINOCOCCOSIS

Abstract :

In recent years, the blood groups of patients have begun to attract the attention of researchers, which is associated with natural selection and genetic load in the human population. Non-random distributions of the alleles of the erythrocyte antigen ABO on the planet have been established, associated with different survival rates of individuals differing in blood type in conditions of frequent epidemics of particularly dangerous infections. The regions of relatively low frequencies of the allele of the first blood group O (I) and relatively high frequencies of the allele of the third group B (III) in Central Asia coincide with the foci of plague, the causative agent of which has an H-antigen, populations with the first blood group, a group especially susceptible to plague. The proof is the fact that relatively high concentrations of the allele of the first group were found in the populations of aborigines of Australia and Polynesia, American Indians, who were practically not infected with the plague. In addition, for populations from the same geographical region, but isolated reproductively, the reason for the sharp difference in the concentration of ABO alleles may be gene drift. For example, the frequency of blood group A (I) reaches 80% among the Indians of the Blackfoot tribe and 20% among the Indians from Utah [Yarygin V.N., 1999]. Our task was to study the susceptibility to pneumonia and parasitic diseases, mainly echinococcosis among healthy and sick children, depending on the blood type. What is the susceptibility to helminthiasis in people of different blood groups.

Full article
Journal ID : TMJ-27-12-2022-11473
Total View : 442

Title : Tumor Surgery Management Prevalence of Computed Tomography, Magnetic Resonance Imaging, And Positron Emission Tomography in Ependymoma Screening Apparatus: A review

Abstract :

The identification of brain cancer is currently vital for clinicians for neurosurgery diagnostic management. Ependymoma cases often appear in toddlers and adults but the diagnostic tools are very diverse. The use of MRI, CT scan and PET tools for ependymoma cases still requires the right way to manage and use them. This study will discuss a review of the diagnosis of MRI, CT scan and PET in cases of ependymoma brain tumors in order to determine their efficiency and management in neurosurgery.

Full article

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