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Teikyo Medical Journal


Journal ID : TMJ-26-08-2022-11386
Total View : 459

Title : Alopecia Areata and its relation to androgenic hormones

Abstract :

Alopecia areata is an autoimmune patchy hair loss often takes shape of a quarter. Many factors participate in its expression. Androgenic hormones are suspected to have role in Alopecia Areata. The aim of this research to assess serum testosterone & estrogen levels in alopecia areata patients. 40 patients alopecia areata lesions (18 females and 22 males; ages varying from 20-45 years and 40 healthy individuals as control group (23 males and 17 females; ages varied from 20–45years) were included. All patients were enrolled from Medical research center of excellence of National Research Centre, Egypt, from (January 2022 to May 2022). AA cases are diagnosed clinically and then can be confirmed by dermoscope. Blood samples were collected from both groups; both testosterone & estrogen were evaluated. Results: The current study stated a significant increase in testosterone levels in males with alopecia areata compared to control, on the other hand no significant increase in estrogen level was noted in females with alopecia areata. Conclusion: Androgenic hormones may have a role in pathogenesis of AA.

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Journal ID : TMJ-25-08-2022-11385
Total View : 400

Title : A Comparison of Apical Microleakage in Open Apex Teeth Using the Mineral Trioxide Aggregate (MTA) and the Modified Portland Cement (MPC): An In-Vitro Study

Abstract :

Endodontic management of open apices often presents a challenge which makes the delivery of root-filling materials difficult, potentially leading to overextension and/or overfilling of the root canal. The aim of this study was to compare the level of apical microleakage between the Mineral Trioxide Aggregate (MTA) and the modified Portland cement (MPC) when utilized as an apical plug. The study sample consisted of 30 permanent, single-rooted human teeth, which was divided into two groups (15 MTA, 15 MPC). The length of the teeth was standardized so the average root length was 13 mm. The external root surfaces of the specimens were completely covered with two coats of nail polish. At that point, all teeth were soaked in methylene blue with the percentage of 2% and in 65% nitric acid. Then the resulting solution was channeled into an Eppendorf tube to be centrifuged in micro-centrifuges. Ultraviolet (UV) spectrophotometer at 550 nm was used as a measurement of optical density or absorbance of the supernatant solution. The mean of dye concentration values were 0.028, 0.032 in the MTA and MPC groups, respectively. No statistical differences in the amount of dye concentration (mg/ml) were observed between the two groups (P >0.05). With the limitation of this study, it was found that there were no statistically significant differences in the microleakage between MPC and MTA. In addition, MPC could be a replacement material of MTA in apical plugs in open apex permanent teeth.

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Journal ID : TMJ-25-08-2022-11384
Total View : 398

Title : Modalities for the management of suicidal patients in liaison psychiatry A one year retrospective study in a Moroccan general hospital

Abstract :

Suicide is one of the leading causes of potentially preventable death among adolescents and young adults. Suicide attempts (SA) can occur within general hospital services. Liaison psychiatry is then at the forefront in the detection and evaluation of suicidal risk in patients treated for potentially disabling organic pathologies and/or for the somatic consequences of a suicide attempt. To determine the profile of suicidal patients seen in liaison psychiatry and the management modalities they underwent, we conducted a retrospective observational study during 2021, within the Mohammed V Military Hospital of Instruction of Rabat. A total of 40 suicidal patients were identified. The median age was 22 years, with a female predominance. Of all study participants, 47.5% had a psychiatric follow-up, 40% had already used psychotropic drugs and 20% had made a previous suicide attempt. Among the services seeking psychiatric consultation, medical-surgical emergencies accounted for 42.5% of cases, surgical services for 25% of patients, and intensive care units for 12.5% of cases. Suicidal thoughts were recorded in 72.5% of cases, verbalization of suicidal ideas in 22.5%, and suicidal behavior in 15%. The most frequently used means of suicide were drug ingestion in 30% of cases, rat poison ingestion in 20% of cases and defenestration in 17.5%. The most frequent diagnoses were adjustment disorder, followed by personality disorder and depressive disorder. Half of the patients had an indication for hospitalization and 47.5% had been kept in the hospital under medical supervision.

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