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27 Jun 2024 (Vol 47 , Iss 06 )

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30 Jun 2024 (Vol 47 , Iss 06 )

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Teikyo Medical Journal


Journal ID : TMJ-11-09-2022-11398
Total View : 407

Title : Evaluation of the efficacy of botulinum toxin type A injection on improving the submandibular approach scars: Randomized controlled trial, Split-Scar

Abstract :

This study aims to evaluate the efficacy of early postoperative injection of botulinum toxin type A (BTA) on improving the submandibular approach scars. Fifteen patients who underwent facial surgery through the submandibular approach were enrolled in this study. On the seventh postoperative day, BTA was randomly injected into one-half of each wound. The other half was injected with the same amount of saline alone. The scars were assessed independently by three surgeons at one, three, and six months postoperatively using the visual analogue scale (VAS), the Vancouver Scar Scale (VSS), and the patient and observer scar assessment scale (PSAS and OSAS). All Fifteen patients have completed the clinical study according to the three follow-up periods. Compared to the half injected with saline only, the BTA treated side showed a noticeable improvement and statistically significant difference in most periods, especially at the six-month follow-up appointment. According to the used scales: VAS, VSS, PSAS and OSAS, the results of statistical tests after six months were as follows (P = 0.001, P = 0.009, P=0.004 P=0.001), respectively. BTA early injection into submandibular approach wounds leads to better-looking submandibular approach scars.

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Journal ID : TMJ-08-09-2022-11396
Total View : 408

Title : Molecular characterisation of HEV and NoV in mussels from Oued El Maleh estuary in Morocco

Abstract :

Hepatitis E virus (HEV) and Norovirus (NoV) are two enteric viruses responsible for mild or acute gastroenteritis and hepatitis. These viruses are known for their resistance to environmental conditions, and transmitted by the consumption of contaminated water. Shellfish produced close to land can bioaccumulate enteric viruses of human and animal origin, including zoonotic hepatitis E virus that infect both human and swine. Hepatitis E virus (HEV) represents one of the principal causative agents of hepatitis, and norovirus (NoV) is the first causative agent of childhood gastroenteritis in the world, globally causing huge healthcare-associated economic losses. The aim of this study was to evaluate HEV and NoV contamination in samples of mussels (Mytilus edulis Linnaeus, 1758) in coastal area of Mohammedia. Indeed 48 batches of samples of blue mussels (n=576 mussels) were collected from three points of at the mouth of the Oued El Maleh were analyzed for the detection of HEV and NoV using RT-PCR in real time. Overall, one (2%) of these samples tested positive for HEV RNA and thirteen (27%) for NoV. To our knowledge, this is the first notification of the detection of HEV and NoV in mussels collected in the mouth of Oued El Maleh. These findings suggest that a health risk may exist for users of waters in the the coast of Mohammedia and to consumers of shellfish. Monitoring HEV and NoV and similar viruses in shellfish can help prevent viral contamination. Further research is needed to assess the sources and infectivity of HEV in these settings, and to evaluate additional shellfish harvesting areas.

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Journal ID : TMJ-06-09-2022-11395
Total View : 462

Title : TOPICAL OZONATED ALOE VERA REDUCE THE INFLAMMATION IN RADIATION DERMATITIS

Abstract :

Radiation dermatitis is a side effect is the most common side effect of external radiation with varied clinical features. Applying topical ozonated aloe vera can reduce the inflammatory reaction in radiation dermatitis by decreasing neutrophil migration and TNF-α expression. This study aims to improve the healing response of radiation dermatitis with ozonated aloe vera therapy based on TNF-α face and the ratio of neutrophils to lymphocytes. Experimental study with post-test only randomized control group design on 36 male Sprague Dawley rats weighing 150±50 grams and given a single dose of 7 Gy radiation. After radiation, acclimatization was carried out for seven days and followed by randomization and divided into six groups, namely negative control, positive control given hydrocortisone cream 2.5%, treatment groups 1, 2, 3, and 4 were given aloe vera, aloe vera, respectively ozonated doses of 300 mg/mL, 600 mg/ml, and 1200 mg/mL for seven days. After the treatment, the rats were terminated, and histological preparations were made with HE staining and immunohistochemistry to see the NL ratio and TNF-α. Three rats were dead on external radiation administration. In the Kruskal-Wallis test, there were significant differences in the NL ratio and TNF-α expression based on the type of treatment (p <0.05). In the Mann-Whitney test, there were significant differences between treatment groups (p < 0.05). Ozonated aloe vera increases radiation dermatitis's healing response in Sprague Dawley rats by decreasing TNF-α expression and neutrophil-lymphocyte ratio.

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Journal ID : TMJ-06-09-2022-11394
Total View : 434

Title : Anti-COVID-19 vaccine movements and the mental unity of the masses

Abstract :

It is useful to view the anti-vaccine movements in the light of current social psychology, psychoanalysis, and biomedical insights. The study of the formation, types, motivations and other characteristics of the psychological masses can guide us in the creation of effective vaccination strategies, important in the context of COVID-19. A search was carried out with the key terms "hesitancy", "refusal", "vaccination", "anti-vaccination", "movement", "social", "psychology", "COVID-19" between the years 2019 and 2022. The Scopus, Google Scholar, Taylor & Francis, Mendeley and PubMed Central databases were consulted. Three hundred and sixty-one documents were retrieved and after filtering, as shown in figure 2, Thirty-three were chosen for the construction of the document. This selected literature was correlated as much as possible with the landmark works of Le Bon and Freud on crowd psychology. The most relevant thing that is analyzed here is the very probable validity today of the ideas of the French doctor and psychologist and the Viennese psychoanalyst in the understanding of the anti-vaccine masses. Helpful ideas from these two authors are also found that serve to complement and improve strategies currently used to promote immunization, and some suggestions for these strategies are given at the end. Credible and influential authorities, government entities, legislation, and health providers must dispel misinformation. They must be supported by experts in marketing, graphic design, etc. so that the contents of pro-vaccination propaganda have a greater impact on people than the media used by the anti-vaccine masses. As expert professionals we must improve strategies to improve the acceptance of vaccination.

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Journal ID : TMJ-03-09-2022-11393
Total View : 418

Title : RELATIONSHIP BETWEEN PHYSICAL ACTIVITY LEVEL AND POSTPARTUM DEPRESSION SYMPTOMS AMONG POSTPARTUM WOMEN IN ENUGU, NIGERIA.

Abstract :

Studies are sparse on the relationship between physical activities and postpartum depression (PPD) in sub-Saharan Africa, particularly Nigeria. The study explored the relationship between Physical activity level (PAL) and PPD among postpartum women in Enugu, Nigeria. 232 postpartum mothers within 1 - 52 weeks postpartum duration completed the Edinburgh Postnatal Depression Scale (EPDS) and Kaiser Physical Activity level (KPAL) Survey questionnaires, which assessed PPD status and PAL, respectively. PAL was measured in four different domains (household/caregiving, occupational activities, active living habits, and participation in sports and exercise. PAL of women who showed PPD symptoms were compared with those that did not. Most of the women showed no symptoms of PPD (65%) and had low PAL (89%). Significant differences did not exist between KPAL scores of PPD positive and negative women (p>0.05). Similarly, there was no significant association (p > 0.05) between their EPDS and KPAL scores. PPD was not prevalent among the study population. And although respondents PAL were not determinants of their reported PPD symptoms, an increase in PAL scores leads to a decrease in EPDS scores which indicates that higher physical activity levels reduce the risk of PPD.

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