05 Jul 2022
31 Jul 2022
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a new coronavirus, which was first detected in Wuhan, China. The high number of cases and the rapid process of infection require fast and accurate detection to establish a diagnosis of COVID-19. The study aimed to obtain the sensitivity and specificity of the SARS-CoV-2 Architect IgG serological test compared to RT-PCR in COVID-19 patients. This study uses a cross-sectional approach to diagnostic testing, using 128 patients obtained at Persahabatan Hospital. This study took place from April 2021 to July 2021 at the Persahabatan Hospital. Patients swabs were taken for RT-PCR and blood drawn for serological testing using the Architect® i2000SR from Abbott. This study obtained Architect sensitivity results of 27.37% (18.72–37.48%) and specificity results of 63.64% (45.12–79.60%), as well as NPV of 23.33% and PPV of 68.42%. Serology tests using Architect have low sensitivity and specificity, so it cannot be used as a screening test in the population.
Pre-eclampsia (PE) is found in 2-8% of pregnancies and is one of the leading causes of mortality and morbidity. Several studies showed an increased cardiovascular risk of PE in the form of hypertension, heart failure, ischemic heart disease, venous thromboembolism and death. This study aims to evaluate all available evidence on the effect that PE with severe features has on long-term cardiovascular risk compared with PE without severe features. PubMed and ProQuest were searched from January 2000 to December 2019 to identify relevant articles. We estimated the risk by using random effect meta-analysis. Twelve studies involving more than three million women were included. Our study showed the pooled relative risks (RRs) for women with a history of severe PE compared with mild PE were 1.32 (95 % confidence interval [CI] 1.13-1.53) for hypertension, 1.74 (95% CI 0.81-3.72) for heart failure, 1.06 (95% CI 0.78-1.43) for ischemic heart disease, 1.20 (95% CI 0.93-1.54) for thromboembolism, 1.46 (95 % CI 0.92-2.32) for cardiovascular hospitalization, and 1.02 (95 % CI 0.73-1.43) for cardiovascular mortality. Other study on ventricular fibrillation could not be pooled. Severe preeclampsia has an increased risk of hypertension by one- to two-fold compared to mild preeclampsia. Women with a history of preeclampsia should be educated about lifestyle modification as well as regular monitoring to reduce the risk of cardiovascular disease. Further consideration and evaluation should be given to preeclampsia with severe features.
Covid-19 has a negative influence on the social, psychological, physical, and mental health of patients such as, increasing the likelihood of nervousness, and post-traumatic stress disorder (PTSD) especially among elderly. The aim of this research was to identify the level of the post-traumatic stress disorder and its impact on quality of life among those who survived the COVID-19 epidemic and their control group, as well as their associated correlates. Comparative cross-sectional research was undertaken among elderly patients (112Covid-19 patients and 112 non Covid-19 patient), including males and females, aged 60 and up. attending outpatient clinics and admitted to geriatric hospital in Ain shams university hospitals. Data collected by using three- sections structured questionnaire including sociodemographic and clinical section, Posttraumatic Stress Disorder Checklist-5 and Older People’s Quality of life Questionnaire. There was statistically significant difference (p <0.05) between elderly suffering from Covid-19 and elderly not suffering from Covid-19 in all items of Quality of Life and in development of post-traumatic stress disorders. In covid-19 group the Post traumatic stress disorders was statistically negative correlate with Quality Of Life, and severity of Covid-19 was significant factor affect it. The research found that QOL and PTSD are critical aspects of older people's life following Covid-19 infection. So There is an urgent need to raise awareness regarding post- COVID PTSD in the elderly population, with better psychological support services, as well as crisis interventions, to help this group cope with anxiety and post-traumatic stress disorder.
Hospitals, as an organization, must implement a survival mechanism. Strategic plans that have been previously devised become guidelines and directions of the organization’s business processes, most of which must undergo changes and adjustments according to the conditions of the coronavirus disease 2019 (COVID-19) pandemic. This review systematically aimed to reevaluate the strategic planning of various hospitals and to evaluate multiple strategic planning aspects that more frequently change during the COVID-19 pandemic. This review is intended to determine whether strategic planning may still be modified and used despite various unexpected events such as the COVID-19 pandemic. Literature searches were initially performed on December 13, 2020. Besides the manual search of some journals in-hospital administration, electronic databases, including Proquest, Scopus, Ebscohost, and Cochrane Library, were explored for articles published in English on the hospital strategic planning used when facing the COVID-19 pandemic. A total of 1448 eligible articles were identified through initial searches, among which 1245 were excluded due to duplication, and 170 articles were excluded as the contents in the title and abstract were irrelevant to this review. The remaining 33 studies were screened again using the inclusion and exclusion criteria. An additional five articles that were not detected in the database search were found from the reference lists of selected articles using manual search. Subsequently, 21 articles were removed after a full-text review. Finally, 17 articles met the inclusion criteria for this review. The framework for determining the level of uncertainty surrounding strategic planning and for tailoring the strategy to that uncertainty. Efforts to respond to pandemics at the outset and then implement strategic steps largely depend on the resilience of hospitals. Strategic planning transformation can be the solution for hospital organizations to be resilient and move forward in an uncertain era.
This study aimed to compare fracture resistance on endodontically treated premolars restored with endocrowns and conventional crowns reinforced with and without fiber posts when subjected to pressure forces. 30 intact premolars were extracted for orthodontic reasons. All teeth had nearly identical dimensions, endodontically treated and divided into three equal groups (10 each). Then all premolar crowns were cut at 2 mm above the CEJ. Group A were restored by glass ceramic reinforced with lithium disilicate (LDS) Endocrowns. Group B were restored by LDS conventional crowns reinforced with fiber posts. Group C were restored by LDS conventional crowns reinforced with a composite build-up without posts. All restorations were cemented by dual cure resin cement and then subjected to pressure test by using a general mechanical testing machine. Each sample was loaded until fracture. The data were recorded by Newton (N). Samples failure modes were examined by stereoscope and radiography. Then the data were statistically analyzed. One-way ANOVA then Bonferroni (Sidak) test were used to determine and reveal any significant differences in fracture strength means between the groups. Chi Square test was also used to analyze the relationship between fracture strength means and failure modes. One-way ANOVA test revealed statistically significant differences between fracture strength means of the studied groups (p> 0.05), and Bonferroni (Sidak) test revealed significant differences between group A (914.2) N and B (734.2) N and between A and C (792.3) N, while there was no statistically significant difference between group B and C. Irreparable fractures were mostly seen in group A due to higher fracture strength means. Endocrowns revealed the highest resistance fracture mean, followed by the classical crowns groups. Endocrowns mostly caused unfavorable failures. Crowns reinforced composite with no posts (group C) showed a preferred behavior, so it is a promising method because of its less invasive approach.