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Teikyo Medical Journal


Journal ID : TMJ-13-12-2021-10880
Total View : 392

Title : ISOTRETINOIN and GLUTATHIONE COMBINATION vs ISOTRETINOIN ALONE ON SEVERE ACNE VULGARIS

Abstract :

Acne vulgaris (AV) is a chronic inflammation of pilosebaceous unit that is common in teenagers. According to its severity degree, AV can be categorized as mild, moderate, and severe. One of its alternative therapies on severe AV is isotretinoin. Oxidative stress affects the formation of acne vulgaris, therefore the antioxidant is considered as an additional therapy. Glutathione is of the antioxidants which has a protective effect on oxidative stress. Two male patients age of 20 years old suffered from severe AV for approximately a year. Both of the patients had several therapies but had not improved, by which one patient being treated with the combination of isotretinoin and glutathione and the other with isotretinoin alone for 4 weeks. Inflammation is one of the factors on the pathogenesis of AV. Isotretinoin as the first retinoid generation which functions as antiinflammation and immunomodulator, is one of the alternative therapies on mild AV. Oxidative stress is one of the causes of inflammation on AV. Glutathione is an antioxidant which functions as a protection to the oxidative stress. There is an improvement on severe-degree AV which treated with the combination of isotretinoin and glutathione as well as with isotretinoin alone.

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Journal ID : TMJ-12-12-2021-10879
Total View : 418

Title : The effectiveness of mobile SMS based counselling method for increasing knowledge and awareness about HIV/AIDS and decreasing patients: a systematic review and meta-analysis protocol

Abstract :

Heterogeneous results have been reported in several studies that use the efficiency of the mobile SMS intervention technique to increase knowledge and awareness about HIV/AIDS and reduction, requiring a systematic review to obtain a comprehensive summary of existing proof. Hence the purpose of this review is to gather accessible proof of the efficiency of the mobile counselling method based on SMS in increasing knowledge and awareness about HIV/AIDS and reducing the number of patients. Searches will be carried out in the PubMed / Medline, Scopus, Google Scholar, Cochrane Library and other articles reviewed up to December 2019 databases. Studies have been included that compare the prevalence of HIV/AIDS among the intervention group that was exposed to mobile SMS based counselling methods and the control group that was not exposed to such intervention. The study's primary outcome is the change in knowledge and awareness about HIV/AIDS and the risk of observed HIV/AIDS prevalence from baseline to post-intervention. It will include randomized controlled designs for study trials. Two independent reviewers will critically appraise selected studies. The data collected will include information on the review's questionnaire and goals about the strategies, populations, research methods and related outcomes. Effect sizes will be expressed as a risk ratio, and their 95 per cent confidence intervals will be determined for analysis. This study and meta-analysis will systematically analyse and incorporate the evidence available on the efficacy of mobile SMS-based counselling method to increase knowledge and awareness about HIV/AIDS and decrease patients. In this review, information will be gathered and summarized on the potential impact of mobile SMS based counselling for increasing knowledge and awareness about HIV/AIDS and decreasing patients. The findings from this study will provide guidance to future research and public health professionals with an understanding of the importance of mobile SMS-based counselling and provide guidelines for applicability of community-based intervention.

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Journal ID : TMJ-12-12-2021-10878
Total View : 413

Title : Prevalence of Obesity-Related Health Disorders Detected During Preoperative Evaluation for Bariatric Surgery

Abstract :

Our research was conducted on 100 patients who underwent bariatric surgery due to morbid obesity in our metabolic and bariatric surgery clinic (Tikrit Hospitals) between October 2017 and March 2021 to determine the diseases that accompany or cause obesity with a multidisciplinary evaluation in the management of patients before bariatric surgery, we think that these determinations will enable us to predict the risk of preoperative mortality and postoperative success. Our research was conducted on 100 patients who underwent bariatric surgery due to morbid obesity in our metabolic and bariatric surgery clinic (Tikrit Hospitals) between October 2017 and March 2021. Anthropometric, physical examination and laboratory data were obtained and recorded retrospectively from the files and electronic records of each case. This research is a cross-sectional descriptive study, which is done by retrospectively examining the data of the patients, their files and electronic records. Our study was carried out in accordance with ethical rules. In the study group, the frequency of the diseases detected during the evaluation of the patients with a BMI > 40 kg / m2 with a multidisciplinary approach before bariatric surgery was used as data. Cases between the ages of 18-65 were included in the study. The records of 100 patients whose files were examined were evaluated. Of the patients, 64% were female, 36% were male, mean age was 48.6 years, and mean BMI was 39.7 kg/m2. In obesity patients, type-2 diabetes was detected in 13% hypertension in 32%, and metabolic syndrome in 64%. For the first time in this study, the prevalence of nodular goiter, thyroid cancer, adrenal adenoma, and gastric cancer before bariatric surgery was detected in obesity patients. Hypothyroidism and subclinical hypothyroidism found in 8% while Hyperthyroidism and subclinical hyperthyroidism recorded in 4%. Sleep Apnea plus Obstructive Sleep Apnea and Nodular goiter present in 48%. Regarding gastrointestinal problems; gallbladder disease 33%, Non-alcoholic fatty liver disease 63% and Gastro-esophageal reflux disease in 25%. In Depression and other Psychological Disorders there was a rate of 55%. Regarding Adrenal gland diseases, Non-functional adrenal adenoma represented in 7% and Cushing and Subclinical Cushing's syndrome in 4%.

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Journal ID : TMJ-11-12-2021-10877
Total View : 398

Title : Nurses Knowledge, Attitude, and Practice Toward Respiratory Distress Syndrome in Neonate at Salah Al-Deen Governorate Hospital

Abstract :

Respiratory distress syndrome is a respiratory condition that affects newborns and is caused by an immature lung and a lack of surfactant. This study aimed to assess the nurse's knowledge, attitude and practice toward respiratory distress syndrome in neonates. A descriptive design study was conducted to assess nurse’s knowledge, attitude and practice toward respiratory distress syndrome in neonates. this study carried out in the neonatal ward in the Salah Al-den governorate hospitals, from the 7th of October 2020 to the 1st of June 2021. A convenience sample of (75) nurses were selected in this study. Self-report questionnaire was constructed by the researcher based on the review of the literature and past experiences studies, Data analysis was estimated and evaluated using of statistical package for social science (SPSS)version25. The result of the study showed that majority of nurses (52%) had graduated from nursing secondary school and (81.3%) of them had no training course about respiratory distress syndrome, and more than half of study group (50%) had low level regarding knowledge, attitudes and practice. The current study concluded that More than half of the nurses in neonatal wards in Salah Al-Deen Governorate hospitals have low levels of knowledge, attitude, and practice regarding respiratory distress syndrome. nurses' knowledge correlated with demographic characteristics (age, education level, level of experience, and gender. nurse’s attitude regarding RDS is affected by their gender, but not affected by Age, level of experience and their level of education. nurses practice regarding RDS is association with their gender and educational level, but not association with their age and level of experience. The majority of nurses in neonatal wards lack of training courses and continuous education regarding Respiratory Distress Syndrome. The study suggests that nurses should participate in ongoing education and training programs.

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Journal ID : TMJ-11-12-2021-10876
Total View : 442

Title : Role of Screening Tests in Prevention: Example Breast Cancer

Abstract :

The country has a high incidence of malignant tumors. The number of contingents of cancer patients registered in specialized institutions amounted to more than 2 million 164 thousand at the end of 2019. In recent years, specialists have achieved certain success in the treatment of malignant neoplasms and, thus, the prognosis of diseases is generally improving. At the same time, the increasing life expectancy of a significant number of patients cannot remain the only criterion for the level of cancer care. In the organization of medical and social care, the most important indicator is the cure rate from malignant neoplasms, which means not only the clinical recovery of patients, but also their return to their previous social status. Cancer pathology is one of the most complex medical and social problems of civilization. This is due to the rapid growth rates, the severity of complications, the specific effect on the body, which is why the role of screening studies is increasing. Lack of oncological alertness among general practitioners, insignificant personal clinical experience of oncological pathology aggravates the difficulties of diagnosis. Therefore, issues of timely diagnosis are the main ones in the treatment, rehabilitation and prevention of cancer.

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