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08 Jul 2022 (Vol 45 , Iss 05 )

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31 Jul 2022 (Vol 45 , Iss 05 )

Journal ID : TMJ-11-10-2021-10715
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Title : Methicillin-resistant Staphylococcus aureus carrying mecA and capsular polysaccharides (CP5) genes from public hospitals in Babylon, Iraq

Abstract :

Methicillin-resistant Staphylococcus aureus (MRSA) is in charge of the common of nosocomial infections and capable of evading the biocidal action of several antimicrobial agents. The objective of this study was to detect isolates of S. aureus carrying mecA and capsular polysaccharides (CP5) gene in Iraq. A total of 180 different clinical samples were collected from patients. Clinical samples involved blood, urine, cerebrospinal fluid, burns, and wounds. Among 180 clinical samples collected, 46 (25.5%) gave positive growth on ordinary culture media and 134 isolates (74.5%) gave no growth and this may be due to fungal or viral infections or antibiotics usage before taking samples. Results revealed that there were five S. aureus isolates carrying mecA gene and one isolate has capsular polysaccharides (CP5) gene. High rate of MRSA Isolates was recovered from the burn unit. MDR was found at a high rate among resistant isolates. Out of 5 clinical isolates of MRSA detected for capsular genotypes, capsular polysaccharides 5 (CP5) were detected in only one isolate (A.MS. isolate). This study represent a first recorded study in Iraq for isolation and detection of MRSA strain carrying capsular polysaccharides (CP5) gene. This MRSA isolate can be further used to produce as a candidate immunogenic compound against S. aureus infection.

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